Located in downtown San Diego, the U.S. Grant recently completed a $52 million renovation. For large events, the Presidential Ballroom measures 9,300 square feet. Outdoor event spaces take the form of two 4,000-square-foot rooftop terraces. Each of the 270 guest rooms boasts a 9-foot-high ceiling and a headboard printed with artwork by Yves Clement. Call 619/232-3121, or visit www.luxurycollection.com/usgrant.com.